EMD-35157

Single-particle
2.85 Å
EMD-35157
3D View Gallery
Deposition: 18/01/2023
Map released: 03/07/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35157

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8i3v summary report (pdf.gz) Map-8i3v FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant escitalopram in an inward-open state at resolution of 2.85 angstrom.

EMD-35157

Single-particle
2.85 Å
EMD-35157
3D View Gallery
Deposition: 18/01/2023
Map released: 03/07/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NET
Fitted models: 8i3v

Deposition Authors: Tan J , Xiao Y , Kong F , Lei J , Yuan Y , Yan C
Molecular basis of human noradrenaline transporter reuptake and inhibition.
Tan J , Xiao Y , Kong F , Zhang X , Xu H, Zhu A , Liu Y, Lei J , Tian B , Yuan Y , Yan C
(2024) Nature , 632 , 921 - 929
PUBMED: 39048818
DOI: doi:10.1038/s41586-024-07719-z
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: