EMD-35042

Single-particle
2.86 Å
EMD-35042
3D View Gallery
Deposition: 26/12/2022
Map released: 01/05/2024
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-35042

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8i0k summary report (pdf.gz) Map-8i0k FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the the 2-oxoglutarate dehydrogenase (E1) with TCAIM complex

EMD-35042

Single-particle
2.86 Å
EMD-35042
3D View Gallery
Deposition: 26/12/2022
Map released: 01/05/2024
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 2-oxoglutarate dehydrogenase, OGDH and T cell activation inhibitor mitochondrial, TCAIM
Fitted models: 8i0k

Deposition Authors: Yu X, Yang W
The mitochondrial DNAJC co-chaperone TCAIM reduces alpha-ketoglutarate dehydrogenase protein levels to regulate metabolism
Wang J, Yu X, Zhong Y, Ma X, Gao Y, Zhou D, Wang J, Fu Y, Fan S, Su J, Huang M, Haigis M, Wang P, Xu Y, Yang W
(2025) Mol Cell , 85 , 638
DOI: doi:10.1016/j.molcel.2025.01.006
ISSN: 1097-2765
ASTM: MOCEFL