EMD-34022

Single-particle
3.9 Å
EMD-34022
3D View Gallery
Deposition: 05/08/2022
Map released: 03/01/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-34022

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7yq8 summary report (pdf.gz) Map-7yq8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide

EMD-34022

Single-particle
3.9 Å
EMD-34022
3D View Gallery
Deposition: 05/08/2022
Map released: 03/01/2024
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ternary complex of human topoisomerase II beta with DNA and etoposide
Fitted models: 7yq8

Deposition Authors: Naganuma M, Ehara H , Kim D, Nakagawa R , Cong A , Bu H, Jeong J, Jang J, Schellenberg MJ , Bunch H , Sekine S
ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes.
Bunch H , Kim D, Naganuma M, Nakagawa R , Cong A , Jeong J, Ehara H , Vu H, Chang JH, Schellenberg MJ , Sekine SI
(2023) Nat Commun , 14 , 8341 - 8341
PUBMED: 38097570
DOI: doi:10.1038/s41467-023-44089-y
ISSN: 2041-1723