EMD-32947

Single-particle
3.9 Å
EMD-32947
3D View Gallery
Deposition: 24/02/2022
Map released: 14/12/2022
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32947

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7x1r summary report (pdf.gz) Map-7x1r FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of human thioredoxin reductase bound by Au

EMD-32947

Single-particle
3.9 Å
EMD-32947
3D View Gallery
Deposition: 24/02/2022
Map released: 14/12/2022
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: THIOREDOXIN REDUCTASE 1
Fitted models: 7x1r

Deposition Authors: He ZS, Cao P
Au4 cluster inhibits human thioredoxin reductase activity via specifically binding of Au to Cys189
Du Z, He Z, Fan J, Huo Y, He B, Wang Y, Sun Q, Niu W, Zhao W, Zhao L, Cao P, Cao K, Xia D, Yuan Q, Liang XJ, Jiang H, Gong Y, Gao X
(2022) Nano Today , 47 , 101686
DOI: doi:10.1016/j.nantod.2022.101686
ISSN: 1878-044X