EMD-32850

Single-particle
3.36 Å
EMD-32850
3D View Gallery
Deposition: 10/02/2022
Map released: 15/06/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32850

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7wv9 summary report (pdf.gz) Map-7wv9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 in complex with Gi protein

EMD-32850

Single-particle
3.36 Å
EMD-32850
3D View Gallery
Deposition: 10/02/2022
Map released: 15/06/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Cannabinoid receptor 1 complexed with Gi heterotrimer proteins
Fitted models: 7wv9

Deposition Authors: Xu Z, Shao Z
Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1.
Yang X, Wang X, Xu Z, Wu C, Zhou Y, Wang Y , Lin G , Li K, Wu M, Xia A , Liu J, Cheng L, Zou J , Yan W , Shao Z , Yang S
(2022) Nat Chem Biol , 18 , 831 - 840
PUBMED: 35637350
DOI: doi:10.1038/s41589-022-01038-y
ISSN: 1552-4469
Grant Support: