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EMD-32298

Single-particle
3.0 Å
EMD-32298
3D View Gallery
Deposition: 26/11/2021
Map released: 22/02/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-32298
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7w40 summary report (pdf.gz) Map and 7w40 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of Human Gastrin Releasing Peptide Receptor in complex with the agonist Bombesin (6-14) [D-Phe6, beta-Ala11, Phe13, Nle14] and Gq heterotrimers

EMD-32298

Single-particle
3.0 Å
EMD-32298
3D View Gallery
Deposition: 26/11/2021
Map released: 22/02/2023
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Peptide Receptor in complex with the agonist Bombesin (6-14) [D-Phe6, beta-Ala11, Phe13, Nle14] and Gq heterotrimers and ScFv16
Fitted models: 7w40

Deposition Authors: Zhan Y , Peng S
Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy.
Peng S, Zhan Y , Zhang D, Ren L, Chen A, Chen ZF , Zhang H
(2023) PNAS , 120 , e2216230120 - e2216230120
PUBMED: 36724251
DOI: doi:10.1073/pnas.2216230120
ISSN: 1091-6490
ASTM: PNASA6