EMD-29783
Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with 8ANC195 and 10-1074
EMD-29783
Single-particle3.16 Å
Deposition: 16/02/2023Map released: 08/11/2023
Last modified: 23/10/2024
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with 8ANC195 and 10-1074
Fitted models: 8g6u
Deposition Authors: Chen Y
,
Zhou F,
Huang R,
Tolbert W,
Pazgier M
Sample: Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with 8ANC195 and 10-1074
Fitted models: 8g6u
Deposition Authors: Chen Y
,
Zhou F,
Huang R,
Tolbert W,
Pazgier M
Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Prevost J ,
Chen Y ,
Zhou F,
Tolbert WD ,
Gasser R ,
Medjahed H,
Nayrac M ,
Nguyen DN,
Gottumukkala S,
Hessell AJ ,
Rao VB ,
Pozharski E,
Huang RK,
Matthies D ,
Finzi A,
Pazgier M
(2023) Nat Commun , 14 , 6710 - 6710
,
Chen Y ,
Zhou F,
Tolbert WD ,
Gasser R ,
Medjahed H,
Nayrac M ,
Nguyen DN,
Gottumukkala S,
Hessell AJ ,
Rao VB ,
Pozharski E,
Huang RK,
Matthies D ,
Finzi A,
Pazgier M
(2023) Nat Commun , 14 , 6710 - 6710
Grant Support:
- Other government: Start-up funds (United States)