EMD-29715

Single-particle
3.19 Å
EMD-29715
3D View Gallery
Deposition: 08/02/2023
Map released: 09/08/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29715
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8g47 summary report (pdf.gz) Map and 8g47 FULL report (pdf.gz)
EMICSS annotations (xml)

KRAS G12C complex with GDP and AMG 510 imaged on a cryo-EM imaging scaffold

EMD-29715

Single-particle
3.19 Å
EMD-29715
3D View Gallery
Deposition: 08/02/2023
Map released: 09/08/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Homo sapiens
Sample: KRAS G12C complex with GDP and AMG 510 imaged on a cryo-EM imaging scaffold
Fitted models: 8g47

Deposition Authors: Castells-Graells R , Sawaya MR , Yeates TO
Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Castells-Graells R , Meador K , Arbing MA , Sawaya MR , Gee M , Cascio D , Gleave E, Debreczeni JE, Breed J, Leopold K , Patel A , Jahagirdar D , Lyons B, Subramaniam S , Phillips C , Yeates TO
(2023) PNAS , 120 , e2305494120 - e2305494120
PUBMED: 37669364
DOI: doi:10.1073/pnas.2305494120
ISSN: 1091-6490
ASTM: PNASA6