EMD-29498

Single-particle
4.46 Å
EMD-29498
3D View Gallery
Deposition: 20/01/2023
Map released: 03/01/2024
Last modified: 31/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29498

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8fw9 summary report (pdf.gz) Map-8fw9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of full-length human NLRC4 inflammasome with C12 symmetry

EMD-29498

Single-particle
4.46 Å
EMD-29498
3D View Gallery
Deposition: 20/01/2023
Map released: 03/01/2024
Last modified: 31/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: the complex of Needle, human NAIP and NLRC4
Fitted models: 8fw9

Deposition Authors: Matico RE, Yu X , Miller R, Somani S , Ricketts MD, Kumar N, Steele RA, Medley Q, Berger S, Faustin B, Sharma S
Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.
Matico RE, Yu X , Miller R, Somani S , Ricketts MD, Kumar N, Steele RA, Medley Q, Berger S, Faustin B, Sharma S
(2024) Nat Struct Mol Biol , 31 , 82 - 91
PUBMED: 38177670
DOI: doi:10.1038/s41594-023-01143-z
ISSN: 1545-9985
Grant Support: