EMD-29026
CryoEM structure of Kappa Opioid Receptor bound to a semi-peptide and Gi1
EMD-29026
Single-particle2.54 Å
Deposition: 06/12/2022Map released: 06/12/2023
Last modified: 04/06/2025
Sample Organism:
Homo sapiens,
Mus musculus,
synthetic construct
Sample: Kappa Opioid Receptor in complex with Gi1 heterotrimer and a peptide ligand
Fitted models: 8feg
Deposition Authors: Fay JF
,
Che T
Sample: Kappa Opioid Receptor in complex with Gi1 heterotrimer and a peptide ligand
Fitted models: 8feg
Deposition Authors: Fay JF
,
Che T
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor.
Muratspahic E,
Deibler K
,
Han J,
Tomasevic N
,
Jadhav KB
,
Olive-Marti AL,
Hochrainer N,
Hellinger R,
Koehbach J,
Fay JF
,
Rahman MH,
Hegazy L,
Craven TW,
Varga BR,
Bhardwaj G,
Appourchaux K
,
Majumdar S
,
Muttenthaler M
,
Hosseinzadeh P
,
Craik DJ
,
Spetea M
,
Che T
,
Baker D
,
Gruber CW
(2023) Nat Commun , 14 , 8064
,
Han J,
Tomasevic N
,
Jadhav KB
,
Olive-Marti AL,
Hochrainer N,
Hellinger R,
Koehbach J,
Fay JF
,
Rahman MH,
Hegazy L,
Craven TW,
Varga BR,
Bhardwaj G,
Appourchaux K
,
Majumdar S
,
Muttenthaler M
,
Hosseinzadeh P
,
Craik DJ
,
Spetea M
,
Che T
,
Baker D
,
Gruber CW
(2023) Nat Commun , 14 , 8064
Grant Support:
