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EMD-28655
ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 2 (RuvC domain unresolved)
EMD-28655
Single-particle2.96 Å
Deposition: 25/10/2022Map released: 05/04/2023
Last modified: 19/06/2024
Sample Organism:
Deinococcus radiodurans R1,
synthetic construct
Sample: ISDra2 TnpB in complex with reRNA and cognate DNA
Fitted models: 8ex9
Deposition Authors: Sasnauskas G
,
Tamulaitiene G
,
Carabias A
,
Karvelis T
,
Druteika G
,
Silanskas A
,
Montoya G
,
Venclovas C
,
Kazlauskas D
,
Siksnys V
Sample: ISDra2 TnpB in complex with reRNA and cognate DNA
Fitted models: 8ex9
Deposition Authors: Sasnauskas G
,
Tamulaitiene G
,
Carabias A
,
Karvelis T
,
Druteika G
,
Silanskas A
,
Montoya G
,
Venclovas C
,
Kazlauskas D
,
Siksnys V
TnpB structure reveals minimal functional core of Cas12 nuclease family.
Sasnauskas G
,
Tamulaitiene G
,
Druteika G
,
Carabias A
,
Silanskas A
,
Kazlauskas D
,
Venclovas C
,
Montoya G
,
Karvelis T
,
Siksnys V
(2023) Nature , 616 , 384 - 389
,
Tamulaitiene G
,
Druteika G
,
Carabias A
,
Silanskas A
,
Kazlauskas D
,
Venclovas C
,
Montoya G
,
Karvelis T
,
Siksnys V
(2023) Nature , 616 , 384 - 389
Grant Support:
- Novo Nordisk Foundation: NNF14CC0001 (Denmark)
- Novo Nordisk Foundation: NNF0024386 (Denmark)
- Novo Nordisk Foundation: NNF17SA0030214 (Denmark)
- Novo Nordisk Foundation: NNF18OC0055061 (Denmark)
