EMD-28577

Single-particle
3.2 Å
EMD-28577
3D View Gallery
Deposition: 14/10/2022
Map released: 07/06/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28577

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8esm summary report (pdf.gz) Map-8esm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human triacylglycerol synthesizing enzyme DGAT1 in complex with T863 inhibitor

EMD-28577

Single-particle
3.2 Å
EMD-28577
3D View Gallery
Deposition: 14/10/2022
Map released: 07/06/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CryoEM density of human diacylglycerol O-acyltransferase 1 in complex with T863 inhibitor
Fitted models: 8esm

Deposition Authors: Sui X , Kun W, Walther T, Farese R , Liao M
Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Sui X , Wang K, Song K, Xu C, Song J, Lee CW , Liao M , Farese Jr RV, Walther TC
(2023) Nat Commun , 14 , 3100 - 3100
PUBMED: 37248213
DOI: doi:10.1038/s41467-023-38934-3
ISSN: 2041-1723