Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-28376

Single-particle
3.4 Å
EMD-28376
3D View Gallery
Deposition: 03/10/2022
Map released: 24/05/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28376
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8eoi summary report (pdf.gz) Map and 8eoi FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of a human EMC:human Cav1.2 channel complex in GDN detergent (ECAB Map 3)

EMD-28376

Single-particle
3.4 Å
EMD-28376
3D View Gallery
Deposition: 03/10/2022
Map released: 24/05/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Oryctolagus cuniculus
Sample: Ternary complex of the human ER membrane protein complex (EMC) with human CaV alpha1C and rabbit CaV beta3
Fitted models: 8eoi

Deposition Authors: Chen Z , Mondal A , Abderemane-Ali F , Minor DL
EMC chaperone-Ca V structure reveals an ion channel assembly intermediate.
Chen Z , Mondal A , Abderemane-Ali F , Jang S, Niranjan S , Montano JL, Zaro BW , Minor Jr DL
(2023) Nature , 619 , 410 - 419
PUBMED: 37196677
DOI: doi:10.1038/s41586-023-06175-5
ISSN: 1476-4687
ASTM: NATUAS