EMD-28086

Single-particle
2.8 Å
EMD-28086
3D View Gallery
Deposition: 08/09/2022
Map released: 09/11/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-28086
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8efo summary report (pdf.gz) Map and 8efo FULL report (pdf.gz)
EMICSS annotations (xml)

PZM21-bound mu-opioid receptor-Gi complex

EMD-28086

Single-particle
2.8 Å
EMD-28086
3D View Gallery
Deposition: 08/09/2022
Map released: 09/11/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Rattus norvegicus, Bos taurus, synthetic construct
Sample: fentanyl bound mu-opioid receptor-G protein complex
Fitted models: 8efo

Deposition Authors: Zhuang Y , Wang Y, Guo S, Zhou XE, Rao Q, He X, He B, Liu J, Zhou Q, Wang X, Liu W, Jiang X, Yang D, Chen X, Jiang Y, Jiang H, Shen J, Melcher K , Wang M, Xie X, Xu HE
Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Zhuang Y , Wang Y, He B, He X, Zhou XE, Guo S, Rao Q, Yang J, Liu J, Zhou Q, Wang X, Liu M, Liu W, Jiang X, Yang D, Jiang H, Shen J, Melcher K , Chen H , Jiang Y, Cheng X, Wang MW, Xie X, Xu HE
(2022) Cell , 185 , 4361 - 4375.e19
PUBMED: 36368306
DOI: doi:10.1016/j.cell.2022.09.041
ISSN: 1097-4172