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EMD-27439
Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with VH domain F6 (focused refinement of RBD and VH F6)
EMD-27439
Single-particle3.04 Å
Deposition: 28/06/2022Map released: 24/08/2022
Last modified: 09/10/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: SARS-CoV-2 Beta (B.1.351) spike protein in complex with VH domain F6
Fitted models: 8di5
Deposition Authors: Zhu X, Saville JW, Mannar D, Berezuk AM, Subramaniam S
Sample: SARS-CoV-2 Beta (B.1.351) spike protein in complex with VH domain F6
Fitted models: 8di5
Deposition Authors: Zhu X, Saville JW, Mannar D, Berezuk AM, Subramaniam S
Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains.
Chen C,
Saville JW,
Marti MM,
Schafer A,
Cheng MH,
Mannar D,
Zhu X,
Berezuk AM,
Banerjee A 
,
Sobolewski MD,
Kim A,
Treat BR,
Da Silva Castanha PM ,
Enick N,
McCormick KD,
Liu X,
Adams C,
Hines MG,
Sun Z,
Chen W,
Jacobs JL,
Barratt-Boyes SM,
Mellors JW,
Baric RS,
Bahar I,
Dimitrov DS,
Subramaniam S,
Martinez DR,
Li W
(2022) iScience , 25 , 104798 - 104798
,
Sobolewski MD,
Kim A,
Treat BR,
Da Silva Castanha PM ,
Enick N,
McCormick KD,
Liu X,
Adams C,
Hines MG,
Sun Z,
Chen W,
Jacobs JL,
Barratt-Boyes SM,
Mellors JW,
Baric RS,
Bahar I,
Dimitrov DS,
Subramaniam S,
Martinez DR,
Li W
(2022) iScience , 25 , 104798 - 104798
Grant Support: