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EMD-27254
SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196
EMD-27254
Single-particle4.2 Å
Deposition: 08/06/2022Map released: 19/10/2022
Last modified: 23/10/2024
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196
Fitted models: 8d8q
Deposition Authors: Du J, Cui J, Pallesen J
Sample: SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196
Fitted models: 8d8q
Deposition Authors: Du J, Cui J, Pallesen J
DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Parzych EM,
Du J,
Ali AR,
Schultheis K,
Frase D,
Smith TRF ,
Cui J,
Chokkalingam N,
Tursi NJ ,
Andrade VM,
Warner BM,
Gary EN ,
Li Y,
Choi J ,
Eisenhauer J,
Maricic I,
Kulkarni A,
Chu JD,
Villafana G,
Rosenthal K,
Ren K,
Francica JR,
Wootton SK ,
Tebas P,
Kobasa D,
Broderick KE,
Boyer JD,
Esser MT ,
Pallesen J ,
Kulp DW ,
Patel A ,
Weiner DB
(2022) Nat Commun , 13 , 5886 - 5886
,
Cui J,
Chokkalingam N,
Tursi NJ ,
Andrade VM,
Warner BM,
Gary EN ,
Li Y,
Choi J ,
Eisenhauer J,
Maricic I,
Kulkarni A,
Chu JD,
Villafana G,
Rosenthal K,
Ren K,
Francica JR,
Wootton SK ,
Tebas P,
Kobasa D,
Broderick KE,
Boyer JD,
Esser MT ,
Pallesen J ,
Kulp DW ,
Patel A ,
Weiner DB
(2022) Nat Commun , 13 , 5886 - 5886
Grant Support:
- DARPA/JPEO-CBRN: HR0011-21-9-0001 (United States)