EMD-26809
KDM2A-nucleosome structure stabilized by H3K36C-UNC8015 covalent conjugate
EMD-26809
Single-particle3.2 Å
Deposition: 29/04/2022Map released: 22/02/2023
Last modified: 12/06/2024
Sample Organism:
Homo sapiens,
synthetic construct
Sample: KDM2A-nucleosome complex stabilized by H3K36C-UNC8015 covalent conjugate
Fitted models: 7uv9
Deposition Authors: Spangler CJ
,
Skrajna A,
Foley CA
,
Budziszewski GR
,
Azzam DN
,
James LI
,
Frye SV
,
McGinty RK
Sample: KDM2A-nucleosome complex stabilized by H3K36C-UNC8015 covalent conjugate
Fitted models: 7uv9
Deposition Authors: Spangler CJ
,
Skrajna A,
Foley CA
,
Budziszewski GR
,
Azzam DN
,
James LI
,
Frye SV
,
McGinty RK
Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Spangler CJ
,
Skrajna A,
Foley CA
,
Nguyen A
,
Budziszewski GR
,
Azzam DN
,
Arteaga EC,
Simmons HC
,
Smith CB
,
Wesley NA
,
Wilkerson EM
,
McPherson JE
,
Kireev D
,
James LI
,
Frye SV
,
Goldfarb D,
McGinty RK
(2023) Nat Chem Biol , 19 , 624 - 632
,
Skrajna A,
Foley CA
,
Nguyen A
,
Budziszewski GR
,
Azzam DN
,
Arteaga EC,
Simmons HC
,
Smith CB
,
Wesley NA
,
Wilkerson EM
,
McPherson JE
,
Kireev D
,
James LI
,
Frye SV
,
Goldfarb D,
McGinty RK
(2023) Nat Chem Biol , 19 , 624 - 632
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM133498 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): F99CA253730 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM139514 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): R01CA010305 (United States)
