EMD-26795

Single-particle
2.4 Å
EMD-26795
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Deposition: 28/04/2022
Map released: 03/08/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26795
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7utz summary report (pdf.gz) Map and 7utz FULL report (pdf.gz)
EMICSS annotations (xml)

Human thyrotropin analog TR1402 bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)

EMD-26795

Single-particle
2.4 Å
EMD-26795
3D View Gallery
Deposition: 28/04/2022
Map released: 03/08/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human TSH analog TR1402 bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)
Fitted models: 7utz

Deposition Authors: Faust B , Cheng Y , Manglik A
Autoantibody mimicry of hormone action at the thyrotropin receptor.
Faust B , Billesbolle CB , Suomivuori CM , Singh I, Zhang K, Hoppe N, Pinto AFM , Diedrich JK, Muftuoglu Y, Szkudlinski MW , Saghatelian A, Dror RO , Cheng Y , Manglik A
(2022) Nature , 609 , 846 - 853
PUBMED: 35940205
DOI: doi:10.1038/s41586-022-05159-1
ISSN: 1476-4687
ASTM: NATUAS