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EMD-26655
Native Lassa glycoprotein in complex with neutralizing antibodies 12.1F and 37.2D
EMD-26655
Single-particle2.75 Å
Deposition: 14/04/2022Map released: 02/11/2022
Last modified: 21/05/2025
Sample Organism:
Homo sapiens,
Lassa virus
Sample: Native Lassa glycoprotein in complex with 12.1F-scFv and 37.2D-scFv
Fitted models: 7uov
Deposition Authors: Li H
,
Saphire EO
Sample: Native Lassa glycoprotein in complex with 12.1F-scFv and 37.2D-scFv
Fitted models: 7uov
Deposition Authors: Li H
,
Saphire EO
A cocktail of protective antibodies subverts the dense glycan shield of Lassa virus.
Li H ,
Buck T ,
Zandonatti M ,
Yin J ,
Moon-Walker A ,
Fang J ,
Koval A,
Heinrich ML,
Rowland MM ,
Diaz Avalos R,
Schendel SL ,
Parekh D ,
Zyla D ,
Enriquez A ,
Harkins S,
Sullivan B ,
Smith V ,
Chukwudozie O ,
Watanabe R ,
Robinson JE,
Garry RF ,
Branco LM ,
Hastie KM ,
Saphire EO
(2022) Sci Transl Med , 14 , eabq0991 - eabq0991
,
Buck T ,
Zandonatti M ,
Yin J ,
Moon-Walker A ,
Fang J ,
Koval A,
Heinrich ML,
Rowland MM ,
Diaz Avalos R,
Schendel SL ,
Parekh D ,
Zyla D ,
Enriquez A ,
Harkins S,
Sullivan B ,
Smith V ,
Chukwudozie O ,
Watanabe R ,
Robinson JE,
Garry RF ,
Branco LM ,
Hastie KM ,
Saphire EO
(2022) Sci Transl Med , 14 , eabq0991 - eabq0991
Grant Support: