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EMD-26486
70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B
EMD-26486
Single-particle2.58 Å
Deposition: 24/03/2022Map released: 18/05/2022
Last modified: 19/03/2025
Sample Organism:
Escherichia coli,
Escherichia coli K-12,
Actinoplanes sp.
Sample: 70S ribosome in an intermediate state of translocation bound to EF-G(GDP) and ArgyrinB
Fitted models: 7ug7
Deposition Authors: Rundlet EJ
,
Wieland M ,
Holm M,
Koller TO ,
Blanchard SC ,
Wilson DN
Sample: 70S ribosome in an intermediate state of translocation bound to EF-G(GDP) and ArgyrinB
Fitted models: 7ug7
Deposition Authors: Rundlet EJ
,
Wieland M ,
Holm M,
Koller TO ,
Blanchard SC ,
Wilson DN
The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Wieland M ,
Holm M,
Rundlet EJ ,
Morici M ,
Koller TO ,
Maviza TP ,
Pogorevc D,
Osterman IA ,
Muller R ,
Blanchard SC ,
Wilson DN
(2022) PNAS , 119 , e2114214119 - e2114214119
,
Holm M,
Rundlet EJ ,
Morici M ,
Koller TO ,
Maviza TP ,
Pogorevc D,
Osterman IA ,
Muller R ,
Blanchard SC ,
Wilson DN
(2022) PNAS , 119 , e2114214119 - e2114214119
Grant Support: