EMD-25758

Single-particle
2.9 Å
EMD-25758
3D View Gallery
Deposition: 19/12/2021
Map released: 03/08/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25758
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7t9i summary report (pdf.gz) Map and 7t9i FULL report (pdf.gz)
EMICSS annotations (xml)

Native human TSH bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)

EMD-25758

Single-particle
2.9 Å
EMD-25758
3D View Gallery
Deposition: 19/12/2021
Map released: 03/08/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Native human TSH bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)
Fitted models: 7t9i

Deposition Authors: Faust B , Cheng Y , Manglik A
Autoantibody mimicry of hormone action at the thyrotropin receptor.
Faust B , Billesbolle CB , Suomivuori CM , Singh I, Zhang K, Hoppe N, Pinto AFM , Diedrich JK, Muftuoglu Y, Szkudlinski MW , Saghatelian A, Dror RO , Cheng Y , Manglik A
(2022) Nature , 609 , 846 - 853
PUBMED: 35940205
DOI: doi:10.1038/s41586-022-05159-1
ISSN: 1476-4687
ASTM: NATUAS