EMD-25748

Single-particle
3.21 Å
EMD-25748
3D View Gallery
Deposition: 17/12/2021
Map released: 25/01/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25748

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7t8x summary report (pdf.gz) Map-7t8x FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of ACh-bound M2R-Go signaling complex in S1 state

EMD-25748

Single-particle
3.21 Å
EMD-25748
3D View Gallery
Deposition: 17/12/2021
Map released: 25/01/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: ACh-bound M2R-GoA-scFv16 complex
Fitted models: 7t8x

Deposition Authors: Xu J , Wang Q, Du Y , Kobilka BK
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.
Xu J , Wang Q, Hubner H, Hu Y , Niu X, Wang H, Maeda S , Inoue A , Tao Y , Gmeiner P , Du Y , Jin C , Kobilka BK
(2023) Nat Commun , 14 , 376 - 376
PUBMED: 36690613
DOI: doi:10.1038/s41467-022-35726-z
ISSN: 2041-1723
Grant Support: