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EMD-25136

Single-particle
7.29 Å
EMD-25136
3D View Gallery
Deposition: 11/10/2021
Map released: 15/12/2021
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25136
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7sht summary report (pdf.gz) Map and 7sht FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of a partially disrupted IgE high affinity receptor complex bound to an omalizumab variant

EMD-25136

Single-particle
7.29 Å
EMD-25136
3D View Gallery
Deposition: 11/10/2021
Map released: 15/12/2021
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Locked complex of IgE-Fc (G335C) and alpha chain of the high affinity IgE receptor (W156C) bound to clone_7 scFV
Fitted models: 7sht

Deposition Authors: Pennington LF , Jardetzky TS
Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Pennington LF , Gasser P , Kleinboelting S , Zhang C, Skiniotis G , Eggel A , Jardetzky TS
(2021) Nat Commun , 12 , 7069 - 7069
PUBMED: 34862384
DOI: doi:10.1038/s41467-021-27397-z
ISSN: 2041-1723