EMD-24954

Helical reconstruction
3.2 Å
EMD-24954
3D View Gallery
Deposition: 23/09/2021
Map released: 09/03/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24954

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7sar summary report (pdf.gz) Map-7sar FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 2

EMD-24954

Helical reconstruction
3.2 Å
EMD-24954
3D View Gallery
Deposition: 23/09/2021
Map released: 09/03/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TMEM106B fibrils, polymorph 2
Fitted models: 7sar

Deposition Authors: Cao Q, Jiang Y
Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43.
Jiang YX , Cao Q, Sawaya MR , Abskharon R, Ge P , DeTure M, Dickson DW , Fu JY , Ogorzalek Loo RR , Loo JA , Eisenberg DS
(2022) Nature , 605 , 304 - 309
PUBMED: 35344984
DOI: doi:10.1038/s41586-022-04670-9
ISSN: 1476-4687
ASTM: NATUAS