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EMD-24868

Single-particle
3.1 Å
EMD-24868
3D View Gallery
Deposition: 13/09/2021
Map released: 03/11/2021
Last modified: 17/11/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24868
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7s6c summary report (pdf.gz) Map and 7s6c FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of modular PKS holo-Lsd14 stalled at the condensation step and bound to antibody fragment 1B2, composite structure

EMD-24868

Single-particle
3.1 Å
EMD-24868
3D View Gallery
Deposition: 13/09/2021
Map released: 03/11/2021
Last modified: 17/11/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Streptomyces lasalocidi
Sample: Dimeric holo-Lsd14 containing docking domains from DEBS module 3 (holo-Lsd14-DD*) bound to two copies each of Fab 1B2 light and heavy chains and NADP, treated with 2-Acetaminoethyl-thio-3-oxobutanoate
Fitted models: 7s6c

Deposition Authors: Bagde SR , Kim C-Y, Fromme JC
Modular polyketide synthase contains two reaction chambers that operate asynchronously.
Bagde SR , Mathews II , Fromme JC , Kim CY
(2021) Science , 374 , 723 - 729
PUBMED: 34735234
DOI: doi:10.1126/science.abi8532
ISSN: 1095-9203
ASTM: SCIEAS