EMD-24518

Single-particle
3.7 Å
EMD-24518
3D View Gallery
Deposition: 23/07/2021
Map released: 22/09/2021
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24518

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7rl6 summary report (pdf.gz) Map-7rl6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of human p97-R155H mutant bound to ADP.

EMD-24518

Single-particle
3.7 Å
EMD-24518
3D View Gallery
Deposition: 23/07/2021
Map released: 22/09/2021
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Full-length Hexameric p97-R155H mutant
Fitted models: 7rl6

Deposition Authors: Caffrey B , Zhu X , Berezuk A, Tuttle K , Chittori S , Subramaniam S
AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
Caffrey B , Zhu X , Berezuk A, Tuttle K , Chittori S , Subramaniam S
(2021) J Biol Chem , 297 , 101187 - 101187
PUBMED: 34520757
DOI: doi:10.1016/j.jbc.2021.101187
ISSN: 1083-351X
ASTM: JBCHA3