EMD-24452

Single-particle
2.8 Å
EMD-24452 Deposition: 15/07/2021
Map released: 12/01/2022
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24452

HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH ATP, IMP, NAD+, OCTAMER-CENTERED

EMD-24452

Single-particle
2.8 Å
EMD-24452 Deposition: 15/07/2021
Map released: 12/01/2022
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Assembly interface of IMPDH1 filament bound to ATP, IMP, NAD+
Fitted models: 7rgm

Deposition Authors: Burrell AL, Kollman JM
IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Burrell AL, Nie C, Said M , Simonet JC, Fernandez-Justel D , Johnson MC , Quispe J, Buey RM , Peterson JR , Kollman JM
(2022) Nat Struct Mol Biol , 29 , 47 - 58
PUBMED: 35013599
DOI: doi:10.1038/s41594-021-00706-2
ISSN: 1545-9985