Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-24081

Single-particle
2.79 Å
EMD-24081
3D View Gallery
Deposition: 21/05/2021
Map released: 10/11/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24081
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7myn summary report (pdf.gz) Map and 7myn FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of p110alpha in complex with p85alpha

EMD-24081

Single-particle
2.79 Å
EMD-24081
3D View Gallery
Deposition: 21/05/2021
Map released: 10/11/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Heterodimer of PIK3CA with PIK3R1
Fitted models: 7myn

Deposition Authors: Liu X, Yang S
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation.
Liu X, Yang S, Hart JR , Xu Y, Zou X, Zhang H, Zhou Q , Xia T, Zhang Y, Yang D , Wang MW , Vogt PK
(2021) PNAS , 118
PUBMED: 34725156
DOI: doi:10.1073/pnas.2109327118
ISSN: 1091-6490
ASTM: PNASA6