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EMD-23949
The insulin receptor ectodomain in complex with a venom hybrid insulin analog - "head" region
EMD-23949
Single-particle3.4 Å
Deposition: 06/05/2021Map released: 16/03/2022
Last modified: 13/11/2024
Sample Organism:
Homo sapiens
Sample: Insulin receptor ectodomain in complex with insulin analog Vh-Ins-HSLQ - focused refinement.
Fitted models: 7mqo
Deposition Authors: Blakely AD, Xiong X
Sample: Insulin receptor ectodomain in complex with insulin analog Vh-Ins-HSLQ - focused refinement.
Fitted models: 7mqo
Deposition Authors: Blakely AD, Xiong X
Symmetric and asymmetric receptor conformation continuum induced by a new insulin.
Xiong X ,
Blakely A ,
Kim JH,
Menting JG,
Schafer IB ,
Schubert HL,
Agrawal R,
Gutmann T ,
Delaine C,
Zhang YW ,
Artik GO ,
Merriman A,
Eckert D,
Lawrence MC ,
Coskun U ,
Fisher SJ,
Forbes BE ,
Safavi-Hemami H ,
Hill CP ,
Chou DH
(2022) Nat Chem Biol , 18 , 511 - 519
,
Blakely A ,
Kim JH,
Menting JG,
Schafer IB ,
Schubert HL,
Agrawal R,
Gutmann T ,
Delaine C,
Zhang YW ,
Artik GO ,
Merriman A,
Eckert D,
Lawrence MC ,
Coskun U ,
Fisher SJ,
Forbes BE ,
Safavi-Hemami H ,
Hill CP ,
Chou DH
(2022) Nat Chem Biol , 18 , 511 - 519
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