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EMD-23918

Single-particle
3.45 Å
EMD-23918
3D View Gallery
Deposition: 30/04/2021
Map released: 10/11/2021
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23918
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7mn8 summary report (pdf.gz) Map and 7mn8 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain bound to Trastuzumab Fab

EMD-23918

Single-particle
3.45 Å
EMD-23918
3D View Gallery
Deposition: 30/04/2021
Map released: 10/11/2021
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Escherichia coli
Sample: NRG1b-bound HER2/HER3 Heterodimer bound to the Trastuzumab Fab in the context of near full-length receptors
Fitted models: 7mn8

Deposition Authors: Diwanji D, Trenker R
Structures of the HER2-HER3-NRG1 beta complex reveal a dynamic dimer interface.
Diwanji D, Trenker R , Thaker TM , Wang F, Agard DA , Verba KA , Jura N
(2021) Nature , 600 , 339 - 343
PUBMED: 34759323
DOI: doi:10.1038/s41586-021-04084-z
ISSN: 1476-4687
ASTM: NATUAS