Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-23453

Single-particle
3.69 Å
EMD-23453 Deposition: 06/02/2021
Map released: 22/09/2021
Last modified: 22/09/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23453

Human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos in the presence of ATP and sub-stoichiometric NMS-873 (Class 1)

EMD-23453

Single-particle
3.69 Å
EMD-23453 Deposition: 06/02/2021
Map released: 22/09/2021
Last modified: 22/09/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos in the presence of ATP and sub-stoichiometric NMS-873

Deposition Authors: Pan M, Yu Y, Liu L, Zhao M
Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Pan M , Yu Y, Ai H, Zheng Q, Xie Y , Liu L , Zhao M
(2021) Nat. Struct. Mol. Biol. , 28 , 614 - 625
PUBMED: 34262183
DOI: doi:10.1038/s41594-021-00617-2
ISSN: 1545-9985