EMD-23276

Single-particle
3.24 Å
EMD-23276
3D View Gallery
Deposition: 11/01/2021
Map released: 20/01/2021
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23276
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7lck summary report (pdf.gz) Map and 7lck FULL report (pdf.gz)
EMICSS annotations (xml)

PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R)

EMD-23276

Single-particle
3.24 Å
EMD-23276
3D View Gallery
Deposition: 11/01/2021
Map released: 20/01/2021
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: GLP-1:Gs complex with small molecule agonist (PF-06882961) bound
Fitted models: 7lck

Deposition Authors: Belousoff MJ, Johnson RM
Evolving cryo-EM structural approaches for GPCR drug discovery.
Zhang X , Johnson RM, Drulyte I , Yu L, Kotecha A , Danev R , Wootten D , Sexton PM, Belousoff MJ
(2021) Structure , 29 , 963
PUBMED: 33957078
DOI: doi:10.1016/j.str.2021.04.008
ISSN: 0969-2126
ASTM: STRUE6