Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-23127
Cryo-EM structure of NTD-directed neutralizing antibody 5-24 in complex with prefusion SARS-CoV-2 spike glycoprotein
EMD-23127
Single-particle3.9 Å
Deposition: 16/12/2020Map released: 24/03/2021
Last modified: 20/11/2024
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: Prefusion SARS-CoV-2 spike glycoprotein in complex with 5-24 Fab
Fitted models: 7l2f
Deposition Authors: Cerutti G
,
Shapiro L
Sample: Prefusion SARS-CoV-2 spike glycoprotein in complex with 5-24 Fab
Fitted models: 7l2f
Deposition Authors: Cerutti G
,
Shapiro L
Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cerutti G ,
Guo Y ,
Zhou T ,
Gorman J ,
Lee M ,
Rapp M ,
Reddem ER ,
Yu J,
Bahna F,
Bimela J,
Huang Y,
Katsamba PS ,
Liu L ,
Nair MS ,
Rawi R,
Olia AS,
Wang P ,
Zhang B,
Chuang GY,
Ho DD,
Sheng Z,
Kwong PD ,
Shapiro L
(2021) Cell Host Microbe , 29 , 819
,
Guo Y ,
Zhou T ,
Gorman J ,
Lee M ,
Rapp M ,
Reddem ER ,
Yu J,
Bahna F,
Bimela J,
Huang Y,
Katsamba PS ,
Liu L ,
Nair MS ,
Rawi R,
Olia AS,
Wang P ,
Zhang B,
Chuang GY,
Ho DD,
Sheng Z,
Kwong PD ,
Shapiro L
(2021) Cell Host Microbe , 29 , 819
Grant Support:
- Other private: Jack Ma Foundation (China)