Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-23119
Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1
EMD-23119
Single-particle3.0 Å
Deposition: 15/12/2020Map released: 10/02/2021
Last modified: 30/10/2024
Sample Organism:
Homo sapiens,
Mus musculus,
Lama glama
Sample: Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1
Fitted models: 7l1v
Deposition Authors: Hong C
,
Byrne NJ
Sample: Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1
Fitted models: 7l1v
Deposition Authors: Hong C
,
Byrne NJ
Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation.
Hong C ,
Byrne NJ ,
Zamlynny B,
Tummala S ,
Xiao L ,
Shipman JM,
Partridge AT ,
Minnick C ,
Breslin MJ,
Rudd MT ,
Stachel SJ ,
Rada VL ,
Kern JC,
Armacost KA,
Hollingsworth SA ,
O'Brien JA,
Hall DL,
McDonald TP,
Strickland C,
Brooun A,
Soisson SM ,
Hollenstein K
(2021) Nat Commun , 12 , 815 - 815
,
Byrne NJ ,
Zamlynny B,
Tummala S ,
Xiao L ,
Shipman JM,
Partridge AT ,
Minnick C ,
Breslin MJ,
Rudd MT ,
Stachel SJ ,
Rada VL ,
Kern JC,
Armacost KA,
Hollingsworth SA ,
O'Brien JA,
Hall DL,
McDonald TP,
Strickland C,
Brooun A,
Soisson SM ,
Hollenstein K
(2021) Nat Commun , 12 , 815 - 815