Sample Organism: Severe acute respiratory syndrome coronavirus 2, synthetic construct
Sample: Complex of Spike S2P glycoprotein with synthetic nanobody Nb11

Deposition Authors: Schoof MS, Faust BF, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesboelle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Desphande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, Garcia-Sastre A, Ott M, Vignuzzi M, Walter P, Manglik A, QCRG Structural Biology Consortium

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.