EMD-22581

Single-particle
3.9 Å
EMD-22581
3D View Gallery
Deposition: 02/09/2020
Map released: 17/02/2021
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22581

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7jzv summary report (pdf.gz) Map-7jzv FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome

EMD-22581

Single-particle
3.9 Å
EMD-22581
3D View Gallery
Deposition: 02/09/2020
Map released: 17/02/2021
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: BRCA1-UbcH5c/BARD1 E3-E2 module bound to nucleosome core particle
Fitted models: 7jzv

Deposition Authors: Witus SR , Burrell AL, Hansen JM, Farrell DP , Dimaio F, Kollman JM , Klevit RE
BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Witus SR , Burrell AL, Farrell DP , Kang J, Wang M, Hansen JM, Pravat A, Tuttle LM , Stewart MD , Brzovic PS , Chatterjee C , Zhao W, DiMaio F, Kollman JM , Klevit RE
(2021) Nat Struct Mol Biol , 28 , 268 - 277
PUBMED: 33589814
DOI: doi:10.1038/s41594-020-00556-4
ISSN: 1545-9985