EMDB < EMD-22576

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

EMD-22576

Single-particle
8.0 Å

EMD-22576

3D View Gallery

Deposition: 02/09/2020
Map released: 28/07/2021
Last modified: 28/07/2021

Overview 3D View Sample Experiment Validation Additional data Links

Overview 3D View Sample Experiment Validation Additional data Links

EMD-22576

Download

TFIIH/Rad4-23-33 Complex in NER focused on Rad4-33

EMD-22576

Single-particle
8.0 Å
EMD-22576

EMD-22576

3D View Gallery

Deposition: 02/09/2020
Map released: 28/07/2021
Last modified: 28/07/2021

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Saccharomyces cerevisiae
Sample: Ternary complex of Saccharomyces cerevisiae TFIIH, DNA damage proteins Rad4-Rad23-Rad33 and N-acetoxy-acetominofluorinated DNA.

Deposition Authors: van Eeuwen T, Murakami K

Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.

van Eeuwen T , Shim Y, Kim HJ , Zhao T , Basu S , Garcia BA, Kaplan CD , Min JH , Murakami K
(2021) Nat Commun , 12 , 3338 - 3338

PUBMED: 34099686
DOI: doi:10.1038/s41467-021-23684-x
ISSN: 2041-1723

Grant Support:

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01-GM123233 (United States)