EMD-22336

Single-particle
3.47 Å
EMD-22336
3D View Gallery
Deposition: 20/07/2020
Map released: 21/07/2021
Last modified: 15/12/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-22336
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7jhg summary report (pdf.gz) Map and 7jhg FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Dorsomorphin (Compound C) and Fab-nanobody

EMD-22336

Single-particle
3.47 Å
EMD-22336
3D View Gallery
Deposition: 20/07/2020
Map released: 21/07/2021
Last modified: 15/12/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Escherichia coli K-12
Sample: Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Dorsomorphin (Compound C) and Fab-nanobody
Fitted models: 7jhg

Deposition Authors: Yan Y , Murkherjee S, Zhou XE , Xu TH , Xu HE , Kossiakoff AA, Melcher K
Structure of an AMPK complex in an inactive, ATP-bound state.
Yan Y , Mukherjee S , Harikumar KG , Strutzenberg TS , Zhou XE , Suino-Powell K, Xu TH , Sheldon RD , Lamp J , Brunzelle JS , Radziwon K, Ellis A , Novick SJ , Vega IE, Jones RG , Miller LJ , Xu HE , Griffin PR , Kossiakoff AA, Melcher K
(2021) Science , 373 , 413 - 419
PUBMED: 34437114
DOI: doi:10.1126/science.abe7565
ISSN: 1095-9203
ASTM: SCIEAS