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EMD-22251
Structure of SARS-CoV-2 spike at pH 4.0
EMD-22251
Single-particle2.4 Å
Deposition: 29/06/2020Map released: 12/08/2020
Last modified: 20/11/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 Spike
Fitted models: 6xlu
Deposition Authors: Tsybovsky Y, Zhou T
,
Olia A,
Kwong PD
Sample: SARS-CoV-2 Spike
Fitted models: 6xlu
Deposition Authors: Tsybovsky Y, Zhou T
,
Olia A,
Kwong PD
Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Zhou T ,
Tsybovsky Y,
Gorman J ,
Rapp M,
Cerutti G ,
Chuang GY,
Katsamba PS ,
Sampson JM ,
Schon A,
Bimela J,
Boyington JC,
Nazzari A ,
Olia AS,
Shi W,
Sastry M,
Stephens T,
Stuckey J,
Teng IT,
Wang P,
Wang S,
Zhang B,
Friesner RA,
Ho DD,
Mascola JR,
Shapiro L,
Kwong PD
(2020) Cell Host Microbe , 28 , 867 - 879.e5
,
Tsybovsky Y,
Gorman J ,
Rapp M,
Cerutti G ,
Chuang GY,
Katsamba PS ,
Sampson JM ,
Schon A,
Bimela J,
Boyington JC,
Nazzari A ,
Olia AS,
Shi W,
Sastry M,
Stephens T,
Stuckey J,
Teng IT,
Wang P,
Wang S,
Zhang B,
Friesner RA,
Ho DD,
Mascola JR,
Shapiro L,
Kwong PD
(2020) Cell Host Microbe , 28 , 867 - 879.e5