EMD-21693

Single-particle
6.2 Å
EMD-21693
3D View Gallery
Deposition: 13/04/2020
Map released: 02/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21693

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6wjg summary report (pdf.gz) Map-6wjg FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma

EMD-21693

Single-particle
6.2 Å
EMD-21693
3D View Gallery
Deposition: 13/04/2020
Map released: 02/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Rattus norvegicus
Sample: PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
Fitted models: 6wjg

Deposition Authors: Lu T-W, Aoto PC
Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Lu TW, Aoto PC , Weng JH , Nielsen C , Cash JN , Hall J , Zhang P , Simon SM , Cianfrocco MA , Taylor SS
(2020) PLoS Biol , 18 , e3001018 - e3001018
PUBMED: 33370777
DOI: doi:10.1371/journal.pbio.3001018
ISSN: 1545-7885