EMD-21549

Single-particle
4.0 Å
EMD-21549
3D View Gallery
Deposition: 13/03/2020
Map released: 17/06/2020
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21549

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6w5v summary report (pdf.gz) Map-6w5v FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

NPC1-NPC2 complex structure at pH 5.5

EMD-21549

Single-particle
4.0 Å
EMD-21549
3D View Gallery
Deposition: 13/03/2020
Map released: 17/06/2020
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NPC1-NPC2 complex at pH 5.5
Fitted models: 6w5v

Deposition Authors: Yan N, Qian HW
Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2.
Qian H , Wu X, Du X , Yao X , Zhao X, Lee J, Yang H, Yan N
(2020) Cell , 182 , 98 - 111.e18
PUBMED: 32544384
DOI: doi:10.1016/j.cell.2020.05.020
ISSN: 1097-4172