EMD-21406

Single-particle
3.39 Å
EMD-21406
3D View Gallery
Deposition: 18/02/2020
Map released: 21/10/2020
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21406

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6vvx summary report (pdf.gz) Map-6vvx FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Mycobacterium tuberculosis WT RNAP transcription initiation intermediate structure with Sorangicin

EMD-21406

Single-particle
3.39 Å
EMD-21406
3D View Gallery
Deposition: 18/02/2020
Map released: 21/10/2020
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis
Sample: Mycobacterium tuberculosis RNAP promoter open complex
Fitted models: 6vvx

Deposition Authors: Lilic M , Boyaci H
The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Lilic M , Chen J , Boyaci H, Braffman N , Hubin EA, Herrmann J, Muller R , Mooney R, Landick R , Darst SA , Campbell EA
(2020) PNAS , 117 , 30423 - 30432
PUBMED: 33199626
DOI: doi:10.1073/pnas.2013706117
ISSN: 1091-6490
ASTM: PNASA6