EMD-21250

Single-particle
3.5 Å
EMD-21250
3D View Gallery
Deposition: 29/01/2020
Map released: 26/08/2020
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21250

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6vno summary report (pdf.gz) Map-6vno FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)

EMD-21250

Single-particle
3.5 Å
EMD-21250
3D View Gallery
Deposition: 29/01/2020
Map released: 26/08/2020
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: The C-terminal half of the Leucine Rich Repeat Kinase 2 (LRRK2) protein.
Fitted models: 6vno

Deposition Authors: Leschziner A, Deniston C, Lahiri I
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Deniston CK, Salogiannis J , Mathea S , Snead DM , Lahiri I, Matyszewski M , Donosa O , Watanabe R , Bohning J , Shiau AK, Knapp S , Villa E , Reck-Peterson SL , Leschziner AE
(2020) Nature , 588 , 344 - 349
PUBMED: 32814344
DOI: doi:10.1038/s41586-020-2673-2
ISSN: 1476-4687
ASTM: NATUAS