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EMD-21147
Cryo-EM structure of the Glucagon-like peptide-1 receptor in complex with G protein, GLP-1 peptide and a positive allosteric modulator
EMD-21147
Single-particle3.3 Å
Deposition: 20/12/2019Map released: 22/07/2020
Last modified: 23/10/2024
Sample Organism:
Homo sapiens,
Lama glama
Sample: Cryo-EM structure of the Glucagon-like peptide-1 receptor in complex with G protein, GLP-1 peptide and a positive allosteric modulator
Fitted models: 6vcb
Deposition Authors: Sun B
,
Feng D
Sample: Cryo-EM structure of the Glucagon-like peptide-1 receptor in complex with G protein, GLP-1 peptide and a positive allosteric modulator
Fitted models: 6vcb
Deposition Authors: Sun B
,
Feng D
Structural insights into probe-dependent positive allosterism of the GLP-1 receptor.
Bueno AB,
Sun B ,
Willard FS ,
Feng D,
Ho JD,
Wainscott DB,
Showalter AD,
Vieth M,
Chen Q ,
Stutsman C,
Chau B,
Ficorilli J,
Agejas FJ,
Cumming GR ,
Jimenez A,
Rojo I,
Kobilka TS,
Kobilka BK ,
Sloop KW
(2020) Nat Chem Biol , 16 , 1105 - 1110
,
Willard FS ,
Feng D,
Ho JD,
Wainscott DB,
Showalter AD,
Vieth M,
Chen Q ,
Stutsman C,
Chau B,
Ficorilli J,
Agejas FJ,
Cumming GR ,
Jimenez A,
Rojo I,
Kobilka TS,
Kobilka BK ,
Sloop KW
(2020) Nat Chem Biol , 16 , 1105 - 1110