EMD-20857

Single-particle
3.71 Å
EMD-20857
3D View Gallery
Deposition: 22/10/2019
Map released: 29/04/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-20857

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6ur8 summary report (pdf.gz) Map-6ur8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor in complex with varenicline

EMD-20857

Single-particle
3.71 Å
EMD-20857
3D View Gallery
Deposition: 22/10/2019
Map released: 29/04/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human alpha4beta2 nicotinic acetylcholine receptor in complex fab fragments and bound to varenicline
Fitted models: 6ur8

Deposition Authors: Alvarez FJD, Mukherjee S, Han S , Ammirati M, Kossiakoff AA
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Mukherjee S, Erramilli SK , Ammirati M, Alvarez FJD, Fennell KF, Purdy MD, Skrobek BM , Radziwon K, Coukos J , Kang Y, Dutka P , Gao X, Qiu X, Yeager M, Eric Xu H, Han S , Kossiakoff AA
(2020) Nat Commun , 11 , 1598 - 1598
PUBMED: 32221310
DOI: doi:10.1038/s41467-020-15363-0
ISSN: 2041-1723