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EMD-20797
Integrin alpha-v beta-8 in complex with latent TGF-beta, Conformation i (Primary map: sharpened. Additional map: unsharpened.)
EMD-20797
Single-particle3.4 Å
Deposition: 02/10/2019Map released: 05/02/2020
Last modified: 02/12/2020
Sample Organism:
Homo sapiens,
Sus scrofa
Sample: Binary complex of Integrin alpha-v beta-8 with Latent TGF-beta-1 (L-TGF-b1)
Deposition Authors: Campbell MG, Cormier A, Cheng Y, Nishimura SL
Sample: Binary complex of Integrin alpha-v beta-8 with Latent TGF-beta-1 (L-TGF-b1)
Deposition Authors: Campbell MG, Cormier A, Cheng Y, Nishimura SL
Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta.
Campbell MG
,
Cormier A
,
Ito S,
Seed RI
,
Bondesson AJ,
Lou J,
Marks JD,
Baron JL,
Cheng Y
,
Nishimura SL
(2020) Cell , 180 , 490 - 501.e16
,
Cormier A
,
Ito S,
Seed RI
,
Bondesson AJ,
Lou J,
Marks JD,
Baron JL,
Cheng Y
,
Nishimura SL
(2020) Cell , 180 , 490 - 501.e16
Grant Support:
- National Institutes of Health/National Heart, Lung, and Blood Institute: U54HL119893 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute: R01HL134183 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute: R01HL113032 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute: S10OD020054 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute: R01GM098672 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute: P41CA196276 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute: S10OD021741 (United States)
