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EMD-20796
Integrin alpha-v beta-8 in complex with Fabs C6-RGD3 and 11D12v2 (Primary map: sharpened, focused refinement. Five additional maps.)
EMD-20796
Single-particle3.56 Å
Deposition: 02/10/2019Map released: 05/02/2020
Last modified: 16/10/2024
Sample Organism:
Mus musculus,
Homo sapiens
Sample: Ternary complex of Integrin alpha-v beta-8 with Fab C6-RGD3 and Fab 11D12v2
Fitted models: 6ujc
Deposition Authors: Campbell MG
,
Cormier A
Sample: Ternary complex of Integrin alpha-v beta-8 with Fab C6-RGD3 and Fab 11D12v2
Fitted models: 6ujc
Deposition Authors: Campbell MG
,
Cormier A
Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta.
Campbell MG
,
Cormier A
,
Ito S,
Seed RI
,
Bondesson AJ,
Lou J,
Marks JD,
Baron JL,
Cheng Y
,
Nishimura SL
(2020) Cell , 180 , 490
,
Cormier A
,
Ito S,
Seed RI
,
Bondesson AJ,
Lou J,
Marks JD,
Baron JL,
Cheng Y
,
Nishimura SL
(2020) Cell , 180 , 490
Grant Support:
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): U54HL119893 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): R01HL113032 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): R01HL134183 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): R01GM098672 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): S10OD020054 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): S10OD021741 (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): P41CA196276 (United States)
