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EMD-19499
Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom
EMD-19499
Single-particle6.25 Å
Deposition: 29/01/2024Map released: 10/04/2024
Last modified: 24/04/2024
Sample Organism:
Homo sapiens,
Schizosaccharomyces pombe,
Amanita phalloides
Sample: Actin-formin-profilin ring complex: the phalloidin-stabilized F-actin barbed end bound by dimeric-Cdc12 and profilin-S71M.
Fitted models: 8rty
Deposition Authors: Oosterheert W
,
Boiero Sanders M ,
Funk J,
Prumbaum D ,
Raunser S ,
Bieling P
Sample: Actin-formin-profilin ring complex: the phalloidin-stabilized F-actin barbed end bound by dimeric-Cdc12 and profilin-S71M.
Fitted models: 8rty
Deposition Authors: Oosterheert W
,
Boiero Sanders M ,
Funk J,
Prumbaum D ,
Raunser S ,
Bieling P
Molecular mechanism of actin filament elongation by formins.
Oosterheert W ,
Boiero Sanders M ,
Funk J,
Prumbaum D ,
Raunser S ,
Bieling P
(2024) Science , 384 , eadn9560 - eadn9560
,
Boiero Sanders M ,
Funk J,
Prumbaum D ,
Raunser S ,
Bieling P
(2024) Science , 384 , eadn9560 - eadn9560
Grant Support:
- Alexander von Humboldt Foundation: (Germany)
- German Research Foundation (DFG): BI 1998/2-1 (Germany)
- European Research Council (ERC): 856118 (European Union)