Electron Microscopy Data Bank

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EMD-19497

Single-particle
4.54 Å

3D View Gallery

Deposition: 29/01/2024
Map released: 10/04/2024
Last modified: 24/04/2024

Overview 3D View Sample Experiment Validation Additional data Links

EMD-19497

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Cryo-EM reconstruction of the formin Cdc12 bound to the barbed end of F-actin (without phalloidin)

EMD-19497

Single-particle
4.54 Å
EMD-19497

3D View Gallery

Deposition: 29/01/2024
Map released: 10/04/2024
Last modified: 24/04/2024

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Homo sapiens, Schizosaccharomyces pombe
Sample: Complex of the dimeric FH2 domain of S. Pombe Cdc12 bound to the barbed end of F-actin.

Deposition Authors: Oosterheert W , Boiero Sanders M , Funk J, Prumbaum D , Raunser S , Bieling P

Molecular mechanism of actin filament elongation by formins.

Oosterheert W , Boiero Sanders M , Funk J, Prumbaum D , Raunser S , Bieling P
(2024) Science , 384 , eadn9560 - eadn9560

PUBMED: 38603491
DOI: doi:10.1126/science.adn9560
ISSN: 1095-9203
ASTM: SCIEAS

Grant Support:

Alexander von Humboldt Foundation: (Germany)
German Research Foundation (DFG): BI 1998/2-1 (Germany)
European Research Council (ERC): 856118 (European Union)