EMD-18978

Single-particle
3.5 Å
EMD-18978
3D View Gallery
Deposition: 25/11/2023
Map released: 11/06/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-18978

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8r7k summary report (pdf.gz) Map-8r7k FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the human UAP56 - TREX-2 complex

EMD-18978

Single-particle
3.5 Å
EMD-18978
3D View Gallery
Deposition: 25/11/2023
Map released: 11/06/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human UAP56 - TREX-2 complex
Fitted models: 8r7k

Deposition Authors: Hohmann U , Graf M , Plaschka C
An ATP-gated molecular switch orchestrates human messenger RNA export.
Hohmann U , Graf M , Tirian L, Pacheco-Fiallos B , Schellhaas U , Fin L, Handler D , Philipps AW, Riabov-Bassat D, Faraway RW , Puhringer T , Szalay MF , Roitinger E , Brennecke J , Plaschka C
(2025) Nature
PUBMED: 41198879
DOI: doi:10.1038/s41586-025-09832-z
ISSN: 1476-4687
ASTM: NATUAS